She attended St.Aloysius College Sixth Form, where together with Loredana Grech, Annalise Bellizzi, Caroline Caruana, Sheryl Camilleri and Michela Scerri formed up the band Karma Skies in December of 2011 for Soiree 2012.
Odelsie is one of the vocalists of the band and also plays the violin or guitar occasionally. Together with the other members Odelsie released a cover of Some Nights by FUN on youtube, this video has more than 18,000 views to date. In September 2013 Karma Skies released their debut single called Bittersweet September.
In 2014 on 7 th and 8 th February in the Malta Eurovision Song Contest 2014 Odelise, with her violin, got a great experance, when she where add on as backing with the singer DeBee , as her team on stage of her song 'Pin The Middle' who placed in the second place with 46 points, after Firelight who win the Festival with total of 63 points.
On 2 September, 2017 Odelsie taken part in L-Għanja tal-Poplu 2017 with the song ‘Narak Kuntent’ lyrics and music by herself. And with this songs placed 4th, and also win the prize of ‘Best Orginal Song’.