She attended St.Aloysius College Sixth Form, where together with Annalise Bellizzi, Caroline Caruana, Odelsie Camilleri, Sheryl Camilleri and Michela Scerri formed up the band Karma Skies in December of 2011 for Soiree 2012.
Loredana is one of the vocalists of the band and, together with the other members Loredana released a cover of Some Nights by FUN on youtube, this video has more than 18,000 views to date. In September 2013 Karma Skies released their debut single called Bittersweet September.
In 2014 on 7 th and 8 th February in the Malta Eurovision Song Contest 2014 Loredana Grech, as vocal, got a great experance, when she where add on as backing with the singer DeBee , as her backing of her song 'Pin The Middle' who placed in the second place with 46 points, after Firelight who win the Festival with total of 63 points.
She loved many different sounding instruments, although she did’t playing in the group , just for fun, when she got a little bit of free time, these include piano, guitar and carinet.
She is studying in the University of Malta and is taking biology B.Ed course.